After taking Modalert 200 mg, it usually begins to function 30 to 60 minutes later. Modafinil, the active component, enters the system rapidly and aids in waking and mental alertness. Within the first hour, the majority of users report more concentration, less weariness, and improved focus. Long-lasting alertness that lasts for up to 10–12 hours often peaks between 2 and 4 hours.

The rate at which Modalert 200 takes action can vary depending on a number of factors, including metabolism, dosage, food intake, and individual susceptibility. Usually taken in the morning or before strenuous tasks, it yields the optimum results.